“In an age of information overload, this book teaches us why and how to do critical thinking and how to apply it to our research and practice. The author, Prof. Robert Friedland’s long, warm, and sincere gaze toward patients, and his sometimes voracious (he uses the word ‘fierce’) pursuit of learning, weave a gem of words that provide physicians and researchers with invaluable experiences that cannot be gained from medical or scientific books. Now, I have to go back to my practice to face the question Prof. Friedland asked me: Why do strokes usually occur on only one side of the brain?” — Dr. Masafumi Ihara , MD PhD, Stroke Neurologist, National Cerebral and Cardiovascular Center, Osaka, Japan

“Reading this book reminded me of the lecture on introduction to internal medicine that began with the Hippocratic Oath. Written by Dr. Friedland, who has extensive clinical experience, this book is a must-read for anyone interested in clinical medicine.” — Takeshi Tabira , MD, author of the Japanese translation of Robert P. Friedland: Unaging, the Four Factors That Impact How You Age, Cambridge University Press, 2022, Professor of Neurology, Juntendo University, Tokyo, Japan